A new era of science-driven skincare arrives in Southeast Asia as The Ritz-Carlton Spa, Millenia Singapore becomes the region’s flagship partner of EPICUTIS®, a revolutionary, pharmaceutical-grade skincare brand developed by U.S.-based biotech innovator Signum Biosciences. This exclusive collaboration marks a bold step forward in the evolution of holistic wellness, where cutting-edge molecular science meets the timeless elegance of The Ritz-Carlton experience.

Luxury Meets Molecular Science
As the first luxury spa in Southeast Asia to feature EPICUTIS®, The Ritz-Carlton Spa Singapore is setting a new benchmark for integrative wellness. The partnership introduces a curated range of facial and body treatments that combine indulgent spa rituals with clinically proven skincare technologies, catering to a growing demand for performance-backed wellness experiences.
These treatments go beyond surface beauty — each therapy is designed to deliver therapeutic efficacy at a cellular level, enhancing both inner balance and outer radiance. The integration of science-based skincare into the spa’s offerings underscores The Ritz-Carlton’s commitment to innovation and the evolving definition of modern luxury living.
“At The Ritz-Carlton, we are committed to anticipating our guests’ needs and continuously innovating,” said Peter Mainguy, General Manager of The Ritz-Carlton, Millenia Singapore. “Our partnership with EPICUTIS® represents a new chapter in luxury wellness — one that blends cutting-edge science with holistic well-being to deliver visible, lasting results.”
Maxwell Stock, Founder & CEO of EPICUTIS®, added: “Singapore’s reputation as a hub of innovation and sophistication makes it the ideal gateway for EPICUTIS® in Southeast Asia. Through this partnership, we’re bringing our science-first philosophy to discerning guests who value both refinement and results.”
The Science Behind EPICUTIS®
Founded on a science-first philosophy, EPICUTIS® is redefining the standards of clean beauty. Developed in Princeton by renowned biophysicist Dr. Jeffry Stock and master formulator Masanori Tamura, EPICUTIS® is the first professional skincare brand to apply pharmaceutical research technologies to topical skincare.
The brand’s patented active ingredients — including TSC, Hyvia®, and DSD — are clinically proven to enhance skin health at the molecular level. All formulations are EWG Verified, non-toxic, and crafted with medical-grade purity standards. With a minimalist “less-is-more” approach, EPICUTIS® emphasizes ingredient transparency and biocompatibility, ensuring safety and efficacy for even the most sensitive skin types.
Exclusive EPICUTIS® Spa Treatments
Guests can now experience a series of bespoke treatments exclusive to The Ritz-Carlton Spa Singapore, designed to deliver both immediate and long-term skin benefits:
Bespoke Facial: A tailored experience using pharmaceutical-grade EPICUTIS® formulas to address individual skin concerns for balanced, healthy skin.
Signature Facial: A luxurious treatment powered by EPICUTIS® patented ingredients ABSO and Hyvia®, promoting radiance, hydration, and resilience.
Brightening Facial: Infused with antioxidant-rich actives, this revitalizing facial restores luminosity and clarity to dull, uneven skin tones.
Mom-to-Be Ritual: A pregnancy-safe, nurturing treatment using the EPICUTIS® Lipid Body Treatment to soothe, nourish, and enhance skin elasticity.
Lipid Full Body Treatment: A deeply restorative full-body experience featuring exfoliation, lymphatic drainage, and hydration to rejuvenate the skin barrier.


A Sanctuary of Tranquility in the Heart of Marina Bay
Surrounded by lush greenery, The Ritz-Carlton Spa Singapore offers an urban sanctuary for rejuvenation. The award-winning spa features ten serene treatment rooms, including an exclusive Ritz-Carlton Spa Suite for couples seeking a romantic escape. Guests can enjoy full access to the spa’s whirlpools, saunas, steam rooms, and Zero Gravity recliners, as well as an outdoor pool overlooking the city skyline.
Complemented by an extensive menu of massages, body therapies, and half-day spa journeys, the spa invites guests to reconnect with body, mind, and spirit in an environment of understated elegance.
